Regulation of T-cell responses by CNS antigen-presenting cells: different roles for microglia and astrocytes

被引:380
作者
Aloisi, F
Ria, F
Adorini, L
机构
[1] Ist Super Sanita, Lab Organ & Syst Pathophysiol, I-00161 Rome, Italy
[2] Catholic Univ Rome, Inst Gen Pathol, I-00168 Rome, Italy
[3] Roche Milano Ric, I-20132 Milan, Italy
来源
IMMUNOLOGY TODAY | 2000年 / 21卷 / 03期
关键词
D O I
10.1016/S0167-5699(99)01512-1
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 [免疫学];
摘要
Analysis of the mechanisms underlying CNS immune surveillance and immunopathology have provided new insights into the intracerebral regulation of immune responses. Here, Francesca Aloisi, Francesco Ria and Luciano Adorini review, the role of CNS antigen presenting cells and focus on the control of Th1 and Th2 responses by microglia and astrocytes.
引用
收藏
页码:141 / 147
页数:7
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