Intrinsic mRNA stability helps compose the inflammatory symphony

被引：29

作者：

Anderson, Paul ^{[1
,2
]}

机构：

[1] Brigham & Womens Hosp, Div Rheumatol Immunol & Allergy, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Boston, MA 02115 USA

来源：

NATURE IMMUNOLOGY | 2009年 / 10卷 / 03期

关键词：

TRISTETRAPROLIN; ALPHA;

D O I：

10.1038/ni0309-233

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The intrinsic stability of mRNA is important in the regulation of gene expression. New data show that the intrinsic stability of tumor necrosis factor-induced mRNA transcripts strongly influences the coordinated expression of genes that promote distinct phases of the inflammatory response.

引用

页码：233 / 234

页数：3

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