Larger Tonic Pupil Size in Young Children With Autism Spectrum Disorder

被引：103

作者：

Anderson, Christa J. ^{[1
]}

Colombo, John ^{[1
]}

机构：

[1] Univ Kansas, Dept Psychol Schiefelbusch, Inst Life Span Studies, Dole Human Dev Ctr, Lawrence, KS 66045 USA

来源：

DEVELOPMENTAL PSYCHOBIOLOGY | 2009年 / 51卷 / 02期

基金：

美国国家科学基金会;

关键词：

autism spectrum disorder; pupillometry; autonomic nervous system; arousal; eye-tracking; early identification; AUTONOMIC NERVOUS-SYSTEM; HEAD CIRCUMFERENCE GROWTH; SLEEP; RESPONSES;

D O I：

10.1002/dev.20352

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The symptoms of Autism Spectrum Disorder (ASD) have been suggested to manifest from atypical functioning of the autonomic nervous system (ANS), leading to altered arousal and atypical processing of salient stimuli. Coherent with this, persons with ASD show heightened autonomic activity, sleep difficulties, and structural and neurochemical alterations within the ANS. Recently, we observed decreased pupil responses to human faces in children with ASD. In the current study, we found differences in baseline (tonic) pupil size, with the ASD group exhibiting a larger pupil size than age-matched controls. Pupil responses are sensitive and reliable measures of ANS functioning, thus, this finding highlights the role of the ANS, and may provide clues about underlying neuropathology. (C) 2008 Wiley Periodicals, Inc. Dev Psychobiol 51: 207-211, 2009.

引用

页码：207 / 211

页数：5

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