New structural perspectives on K+ channel gating

被引：27

作者：

Perozo, E ^{[1
]}

机构：

[1] Univ Virginia, Dept Mol Physiol & Biol Phys, Charlottesville, VA 22906 USA

来源：

STRUCTURE | 2002年 / 10卷 / 08期

关键词：

D O I：

10.1016/S0969-2126(02)00812-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ion channel gating is a two-stage process. It involves an initial energy transduction step, sensitive to a variety of physical stimuli (voltage, ligand binding, and tension), followed by the structural rearrangements that allow ion permeation. New structural data provides fresh information on both steps and offers unprecedented insight into how ion channels open and close at the molecular level.

引用

页码：1027 / 1029

页数：3

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