Analysis of gene expression profile during 3T3-L1 preadipocyte differentiation

被引：101

作者：

Guo, XM

Liao, K ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Life Sci Res Ctr, Shanghai 200031, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Biochem, Shanghai 200031, Peoples R China

来源：

GENE | 2000年 / 251卷 / 01期

关键词：

3T3-L1; adipocyte; adipogenesis; adipocyte specific genes; cDNA/EST microarray;

D O I：

10.1016/S0378-1119(00)00192-X

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Cellular differentiation is a process in which a group of differentiation specific genes is programmatically induced. This gene expression program leads to changes in both cellular morphological and physiological phenotypes. Using an 18,376-member cDNA/EST microarray, we analyzed the difference in gene expression profiles between differentiated 3T3-L1 adipocyte and nondifferentiated 3T3-L1 preadipocyte. From our study a large number of genes and ESTs were identified as differentially induced or suppressed. In this paper we describe the changes of gene expression profile during 3T3-L1 cell differentiation. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：45 / 53

页数：9

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