Grafted poly(ethylene oxide) brushes as nonfouling surface coatings

被引：276

作者：

Leckband, D ^{[1
]}

Sheth, S

Halperin, A

机构：

[1] Univ Illinois, Dept Chem Engn, Urbana, IL 61801 USA

[2] CEA, DRFMS, SI3M, UMR 5819,CNRS,UJF, F-38054 Grenoble 9, France

来源：

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION | 1999年 / 10卷 / 10期

关键词：

poly(ethylene oxide); protein resistance; water-soluble polymers; oligoethylene oxide; force measurements;

D O I：

10.1163/156856299X00720

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The identification of design criteria for the prevention of surface fouling by protein adsorption has been an elusive research goal. The current ideas in this domain assume two different directions. One focuses on correlating protein adsorption with macroscopic surface properties such as the water wettability. The second approach involves tailoring the molecular interactions between the adsorbing proteins and the surface. In this paper, we focus on the experimental results and theoretical ideas concerned with tuning the interfacial forces by means of terminally grafted PEO chains.

引用

页码：1125 / 1147

页数：23

共 71 条

[1] PROTEIN PARTITIONING IN 2-PHASE AQUEOUS POLYMER SYSTEMS .3. A NEUTRON-SCATTERING INVESTIGATION OF THE POLYMER-SOLUTION STRUCTURE AND PROTEIN POLYMER INTERACTIONS [J].