Heterogeneous enantioselective catalyzed carbonyl- and imino-ene reactions using copper bis(oxazoline) zeolite Y

被引：86

作者：

Caplan, NA

Hancock, FE

Page, PCB

Hutchings, GJ

机构：

[1] Cardiff Univ, Dept Chem, Cardiff CF10 3TB, S Glam, Wales

[2] Johnson Matthey Catalysts, Cambridge CB4 0FP, England

[3] Loughborough Univ Technol, Dept Chem, Loughborough LE11 3TU, Leics, England

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 13期

关键词：

C-C coupling; enantioselectivity; ene reaction; heterogeneous catalysis; zeolites;

D O I：

10.1002/anie.200352534

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A recovery discovery: A simple pathway for the synthesis of α-hydroxy and α-amino carbonyl compounds with good yields and high enantioselection is provided by the first heterogeneously catalyzed enantioselective carbonyl-ene and imino-ene reactions. The catalyst is a bis(oxazoline)-modified CuH zeolite Y (Cu-HY) system (see scheme; Rox = CH3,H; Rbrg = Ph,C(CH3)3), which can easily be recovered and reused.

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页码：1685 / 1688

页数：4

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