Tea consumption and myocardial mortality after acute infarction

被引:138
作者
Mukamal, KJ
Maclure, M
Muller, JE
Sherwood, JB
Mittleman, MA
机构
[1] Beth Israel Deaconess Med Ctr, Div Gen Med & Primary Care, Boston, MA 02215 USA
[2] Beth Israel Deaconess Med Ctr, Div Cardiol, Boston, MA 02215 USA
[3] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
[4] Massachusetts Gen Hosp, Div Cardiol, Boston, MA 02114 USA
[5] Harvard Univ, Sch Publ Hlth, Dept Hlth & Social Behav, Boston, MA 02115 USA
关键词
mortality; myocardial infarction; nutrition;
D O I
10.1161/01.CIR.0000017201.88994.F7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background-Some studies have suggested that tea consumption may be associated with lower mortality among individuals with cardiovascular disease, but the effects of tea consumption on mortality after acute myocardial infarction are unknown. Methods and Results-As part of the Determinants of Myocardial Infarction Onset Study, we performed a prospective cohort study of 1900 patients hospitalized with a confirmed acute myocardial infarction between 1989 and 1994, with a median follow-up of 3.8 years. Trained interviewers assessed self-reported usual weekly caffeinated tea consumption during the year before infarction with a standardized questionnaire. We compared long-term mortality according to tea consumption using Cox proportional hazards regression. Of the 1900 patients, 10 19 consumed no tea (nondrinkers), 615 consumed < 14 cups per week (moderate tea drinkers), and 266 consumed 14 or more cups per week (heavy tea drinkers). Compared with nondrinkers, age- and sex-adjusted mortality was lower among moderate tea drinkers (hazard ratio, 0.69; 95% Cl, 0.53 to 0.89) and heavy tea drinkers (hazard ratio, 0.61; 95% Cl, 0.42 to 0.86). Additional adjustment for clinical and sociodemographic characteristics did not appreciably alter this association (hazard ratio, 0.72; 95% Cl, 0.55 to 0.94 for moderate tea drinkers; hazard ratio, 0.56; 95%, Cl, 0.37 to 0.84 for heavy tea drinkers). The association of tea and mortality was similar for total and cardiovascular mortality. Conclusions-Self-reported tea consumption in the year before acute myocardial infarction is associated with lower mortality after infarction.
引用
收藏
页码:2476 / 2481
页数:6
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