Derivatization methods for the determination of organotin compounds in environmental samples

In the analysis of organotin compounds, derivatization is required in order to achieve more volatile compounds prior to the use of techniques based on CC separation. Derivatization can be considered as one of the main critical steps in organotin analysis, since low yields of derivatization and losses of analytes can easily occur at this stage, and lead to an underestimation of their content in environmental samples. Furthermore, experimental conditions which are not perfectly under control may induce degradations, and alter the original speciation in the sample. Hydride generation, and alkylation by Grignard reagents or by NaBEt4, are the derivatization methods usually applied for organotins. The advantages and disadvantages of these methods are reported. (C) 2000 Elsevier Science B.V. All rights reserved.