Noninvasive measurement of time-varying three-dimensional relative pressure fields within the human heart

被引：96

作者：

Ebbers, T ^{[1
]}

Wigström, L

Bolger, AF

Wranne, B

Karlsson, M

机构：

[1] Linkoping Univ, Dept Med & Care, SE-58185 Linkoping, Sweden

[2] Linkoping Univ, Dept Biomed Engn, SE-58185 Linkoping, Sweden

[3] Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USA

来源：

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME | 2002年 / 124卷 / 03期

关键词：

D O I：

10.1115/1.1468866

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Understanding cardiac blood flow patterns is important in the assessment of cardiovascular function. Three-dimensional flow and relative pressure fields within the human left ventricle are demonstrated by combining velocity measurements with computational mechanics methods. The velocity field throughout the left atrium and ventricle of a normal human heart is measured using time-resolved three-dimensional phase-contrast MRI. Subsequently, the time-resolved three-dimensional relative pressure is calculated from this velocity field using the pressure Poisson equation. Noninvasive simultaneous assessment of cardiac pressure and flow phenomena is an important new tool for studying cardiac fluid dynamics.

引用

页码：288 / 293

页数：6

共 41 条

[1]

Anderson DA, 1984, COMPUTATIONAL FLUID

[2]

Anderson J. D., 1995, Computational Fluid Dynamics, V206

[3] A fast Poisson solver of arbitrary order accuracy in rectangular regions [J].

Averbuch, A ;

Israeli, M ;

Vozovoi, L .

SIAM JOURNAL ON SCIENTIFIC COMPUTING, 1998, 19 (03) :933-952

[4] FLUID MECHANICS OF MITRAL VALVE [J].

BELLHOUSE, BJ ;

BELLHOUSE, FH .

NATURE, 1969, 224 (5219) :615-+

[5] Concomitant gradient terms in phase contrast MR: Analysis and correction [J].

Bernstein, MA ;

Zhou, XHJ ;

Polzin, JA ;

King, KF ;

Ganin, A ;

Pelc, NJ ;

Glover, GH .

MAGNETIC RESONANCE IN MEDICINE, 1998, 39 (02) :300-308

[6] PHYSIOLOGICAL EARLY DIASTOLIC INTRAVENTRICULAR PRESSURE-GRADIENT IS LOST DURING ACUTE MYOCARDIAL-ISCHEMIA [J].

COURTOIS, M ;

KOVACS, SJ ;

LUDBROOK, PA .

CIRCULATION, 1990, 81 (05) :1688-1696

[7] TRANSMITRAL PRESSURE-FLOW VELOCITY RELATION - IMPORTANCE OF REGIONAL PRESSURE-GRADIENTS IN THE LEFT-VENTRICLE DURING DIASTOLE [J].

COURTOIS, M ;

KOVACS, SJ ;

LUDBROOK, PA .

CIRCULATION, 1988, 78 (03) :661-671

[8] Precision of magnetic resonance velocity and acceleration measurements: Theoretical issues and phantom experiments [J].

Durand, EP ;

Jolivet, O ;

Itti, E ;

Tasu, JP ;

Bittoun, J .

JOURNAL OF MAGNETIC RESONANCE IMAGING, 2001, 13 (03) :445-451

[9] Estimation of relative cardiovascular pressures using time-resolved three-dimensional phase contrast MRI [J].

Ebbers, T ;

Wigström, L ;

Bolger, AF ;

Engvall, J ;

Karlsson, M .

MAGNETIC RESONANCE IN MEDICINE, 2001, 45 (05) :872-879

[10]

EBBERS T, 2001, LINKOPING STUDIES SC, V690

← 1 2 3 4 5 →