Sleep disturbance in haemodialysis patients is closely related to depression

Objective: To investigate the relationship between depression and disturbed sleep in haemodialysis patients (HP), and its relative contribution in the development of reported sleep problems. Method: A total of 10 1 patients suffering from end-stage renal disease (ESRD) were assessed through the Athens Insomnia Scale (AIS) for potential sleep problems. Anxiety and depression were evaluated with the Hospital Anxiety and Depression Scale (HADS), and their health-related quality of life and functional status were assessed through the Short Form-36 questionnaire (SF-36). Socio-demographic, anthropometric and clinical data along with a series of biochemical measures were also collected. Results: Multiple logistic regression analysis showed that the independent predictors associated with insomnia in ESRD patients were female sex (OR=7.58) and depression as measured by the HADS (OR=2.59). Conclusion: Incorporating a standard assessment and eventually treatment of depressive symptoms into the care provided to haemodialysis patients might improve psychological well-being, insomnia and quality of life, and, consequently, reduce mortality risk ill this population. (C) 2009 Elsevier Inc. All rights reserved.