The apparent antipsychotic action of the 5-HT2a receptor antagonist M100907 in a mouse model of schizophrenia is counteracted by ritanserin - Rapid communication

被引:37
作者
Martin, P
Waters, N
Carlsson, A
Carlsson, ML
机构
[1] Department of Pharmacology, Göteborg University
[2] Department of Pharmacology, Göteborg University, S-413 90 Göteborg
关键词
MK-801; locomotion; ritanserin; M100907;
D O I
10.1007/BF01277672
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The apparent antipsychotic action of the selective 5-HT2a receptor antagonist M100907 in MK-801-treated NMRI mice was shown to be markedly counteracted by the 5-HT2a/2c receptor antagonist ritanserin. The mechanism of action and potential implications are discussed.
引用
收藏
页码:561 / 564
页数:4
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