C-peptide in the natural history of type 1 diabetes

被引：45

作者：

Palmer, Jerry P. ^{[1
,2
]}

机构：

[1] Vet Affairs Puget Sound Hlth Care Syst, Dept Med, Seattle, WA USA

[2] Univ Washington, Seattle, WA 98195 USA

来源：

DIABETES-METABOLISM RESEARCH AND REVIEWS | 2009年 / 25卷 / 04期

关键词：

BETA-CELL FUNCTION; ANTI-CD3; MONOCLONAL-ANTIBODY; INSULIN-SECRETION; BLOOD-FLOW; ONSET; DYSFUNCTION; GLUCOSE; TRIAL; NEUROPATHY; THERAPY;

D O I：

10.1002/dmrr.943

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Type 1 diabetes is diagnosed when the patient's endogenous insulin secretion decreases to a level which results in hyperglycemia. After diagnosis, insulin secretion continues to decline. As a reference for clinical trials trying to preserve endogenous beta-cell function in patients with recently diagnosed type 1 diabetes, in this short review I attempt to Summarize the natural history of endogenous beta-cell function after the diagnosis of type 1 diabetes. Copyright (C) 2009 John Wiley & Sons, Ltd.

引用

页码：325 / 328

页数：4

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