Input virion proteins: Cryptic targets of antivector immune responses in preimmunized subjects

被引:18
作者
Lowenstein, PR [1 ]
机构
[1] Univ Calif Los Angeles, Cedars Sinai Med Ctr, Gene Therapeut Res Inst, Los Angeles, CA 90048 USA
[2] Univ Calif Los Angeles, Dept Med, Los Angeles, CA 90024 USA
关键词
D O I
10.1016/j.ymthe.2004.05.019
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:771 / 774
页数:4
相关论文
共 25 条
[1]   Pre-existing immunity to adenovirus does not prevent tumor regression following intratumoral administration of a vector expressing IL-12 but inhibits virus dissemination [J].
Bramson, JL ;
Hitt, M ;
Gauldie, J ;
Graham, FL .
GENE THERAPY, 1997, 4 (10) :1069-1076
[2]   Herpes simplex virus vectors elicit durable immune responses in the presence of preexisting host immunity [J].
Brockman, MA ;
Knipe, DM .
JOURNAL OF VIROLOGY, 2002, 76 (08) :3678-3687
[3]   Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus [J].
Duan, DS ;
Yue, YP ;
Yan, ZY ;
Yang, JS ;
Engelhardt, JF .
JOURNAL OF CLINICAL INVESTIGATION, 2000, 105 (11) :1573-1587
[4]   The role of the adenovirus protease in virus entry into cells [J].
Greber, UF ;
Webster, P ;
Weber, J ;
Helenius, A .
EMBO JOURNAL, 1996, 15 (08) :1766-1777
[5]   Signalling in viral entry [J].
Greber, UF .
CELLULAR AND MOLECULAR LIFE SCIENCES, 2002, 59 (04) :608-626
[6]   Repeat transduction in the mouse lung by using adeno-associated virus vectors with different serotypes [J].
Halbert, CL ;
Rutledge, EA ;
Allen, JM ;
Russell, DW ;
Miller, AD .
JOURNAL OF VIROLOGY, 2000, 74 (03) :1524-1532
[7]   Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression:: Implications for gene therapy [J].
Kafri, T ;
Morgan, D ;
Krahl, T ;
Sarvetnick, N ;
Sherman, L ;
Verma, I .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (19) :11377-11382
[8]   Inflammation and adaptive immune responses to adenoviral vectors injected into the brain: peculiarities, mechanisms, and consequences [J].
Lowenstein, PR ;
Castro, MG .
GENE THERAPY, 2003, 10 (11) :946-954
[9]   Virology and immunology of gene therapy, or virology and immunology of high MOI infection with detective viruses [J].
Lowenstein, PR .
GENE THERAPY, 2003, 10 (11) :933-934
[10]   An improved helper-dependent adenoviral vector allows persistent gene expression after intramuscular delivery and overcomes preexisting immunity to adenovirus [J].
Malone, D ;
Della Rocca, C ;
Giannetti, P ;
D'Arrigo, R ;
Liberatoscioli, L ;
Franlin, LL ;
Sandig, V ;
Ciliberto, G ;
La Monica, N ;
Savino, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (11) :5986-5991