WebLogo: A sequence logo generator

被引：9348

作者：

Crooks, GE

Hon, G

Chandonia, JM

Brenner, SE ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Plant & Microbial Biol, Berkeley, CA 94720 USA

[2] Lawrence Berkeley Lab, Berkeley Struct Genomics Ctr, Phys Biosci Div, Berkeley, CA 94720 USA

来源：

GENOME RESEARCH | 2004年 / 14卷 / 06期

关键词：

D O I：

10.1101/gr.849004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

WebLogo generates sequence logos, graphical representations of the patterns within a multiple sequence alignment. Sequence logos provide a richer and more precise description of sequence similarity than consensus sequences and can rapidly reveal significant features of the alignment otherwise difficult to perceive. Each logo consists of stacks of letters, one stack for each position in the sequence. The overall height of each stack indicates the sequence conservation at that position (measured in bits), whereas the height of symbols within the stack reflects the relative frequency of the corresponding amino or nucleic acid at that position. WebLogo has been enhanced recently with additional features and options, to provide a convenient and highly configurable sequence logo generator. A command line interface and the complete, open WebLogo source code are available for local installation and customization.

引用

页码：1188 / 1190

页数：3

共 25 条

[1]

Bateman A, 2004, NUCLEIC ACIDS RES, V32, pD138, DOI [10.1093/nar/gkp985, 10.1093/nar/gkr1065, 10.1093/nar/gkh121]

[2] STRUCTURAL BASIS OF DNA - PROTEIN RECOGNITION [J].