The growth of primary low-grade B-cell gastric lymphoma is sustained by Helicobacter pylori

被引：27

作者：

Cammarota, G ^{[1
]}

Tursi, A ^{[1
]}

Papa, A ^{[1
]}

Voso, MT ^{[1
]}

Serra, F ^{[1
]}

Chiusolo, P ^{[1
]}

Fedeli, G ^{[1
]}

Gasbarrini, G ^{[1
]}

机构：

[1] UNIV CATTOLICA SACRO CUORE, POLICLIN A GEMELLI, INST PATHOL, DEPT HEMATOL, I-00168 ROME, ITALY

来源：

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY | 1997年 / 32卷 / 03期

关键词：

eradication; growth; Helicobacter pylori; mucosa-associated lymphoid tissue lymphoma; management; polymerase chain reaction; treatment;

D O I：

10.3109/00365529709000208

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background: The growth of primary low-grade B-cell gastric mucosa-associated lymphoid tissue (MALT) lymphoma is an antigen-dependent process. Case: We were able to document the influence of Helicobacter pylori on the natural history of primary low-grade B-cell gastric MALT lymphoma in a case investigated by means of polymerase chain reaction for IgH rearrangement. In this case the presence or absence of the bacterium appeared to affect both clinical manifestations and histologic features of the neoplasia, with an acceleration or a slowing down of the neoplastic expansion, respectively. Conclusions: We identified H. pylori as an antigenic stimulus that supports the growth of MALT-type lymphoma. This finding enables us to make some considerations about the management of the disease.

引用

页码：285 / 287

页数：3

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