Recent studies implicate the vacuolar protein-sorting pathway in the transport of the retroviral structural precursor (Gag) protein to its budding site on the plasma membrane of infected cells. This exploitation of the cellular endocytic trafficking machinery to release viral particles could lead to the identification of virus-specific modulators and provide opportunities to design new targeted anti-viral agents.
机构:Univ Calif San Diego, Sch Med, Div Cellular & Mol Med, La Jolla, CA 92093 USA
Katzmann, DJ
Babst, M
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机构:Univ Calif San Diego, Sch Med, Div Cellular & Mol Med, La Jolla, CA 92093 USA
Babst, M
Emr, SD
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机构:
Univ Calif San Diego, Sch Med, Div Cellular & Mol Med, La Jolla, CA 92093 USAUniv Calif San Diego, Sch Med, Div Cellular & Mol Med, La Jolla, CA 92093 USA
机构:Univ Calif San Diego, Sch Med, Div Cellular & Mol Med, La Jolla, CA 92093 USA
Katzmann, DJ
Babst, M
论文数: 0引用数: 0
h-index: 0
机构:Univ Calif San Diego, Sch Med, Div Cellular & Mol Med, La Jolla, CA 92093 USA
Babst, M
Emr, SD
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Diego, Sch Med, Div Cellular & Mol Med, La Jolla, CA 92093 USAUniv Calif San Diego, Sch Med, Div Cellular & Mol Med, La Jolla, CA 92093 USA