Sequential hydrostannylation-cyclisation of delta- and omega-allenyl aryl halides. Cyclisation at the proximal carbon.

被引：33

作者：

Grigg, R

Sansano, JM

机构：

[1] School of Chemistry, Leeds University

来源：

TETRAHEDRON | 1996年 / 52卷 / 42期

关键词：

D O I：

10.1016/0040-4020(96)00801-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium catalysed hydrostannylation of (Bu(3)SnH, THF, degrees C) of delta- and omega-allenyl aryl halides followed by mono- or bis-cyclisation (MeCN, 80 degrees C) affords small (5-7), large (11-17) and spirocyclic rings in which cyclisation occurs at the proximal carbon of the original allene. The reaction proceeds via stereoselective allylstannane formation. The cyclisation products are alpha-vinyl oxygen- and nitrogen-heterocycles. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：13441 / 13454

页数：14

共 31 条

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