Hemodynamic changes in simple partial epilepsy:: A functional MRI study

被引：34

作者：

Krings, T

Töpper, R

Reinges, MHT

Foltys, H

Spetzger, U

Chiappa, KH

Gilsbach, JM

Thron, A

机构：

[1] Aachen Tech Univ, Univ Hosp, Dept Neuroradiol, D-52057 Aachen, Germany

[2] Aachen Tech Univ, Univ Hosp, Dept Neurol, D-52057 Aachen, Germany

[3] Aachen Tech Univ, Univ Hosp, Interdisciplinary Ctr Clin Res Cent Nervous Syst, D-52057 Aachen, Germany

[4] Aachen Tech Univ, Univ Hosp, Dept Neurosurg, D-52057 Aachen, Germany

[5] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Neurol,Clin Neurophysiol Lab, Boston, MA USA

来源：

NEUROLOGY | 2000年 / 54卷 / 02期

关键词：

MRI; functional MRI; MR signal time course; epilepsy; cerebral hemodynamics;

D O I：

10.1212/WNL.54.2.524

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We performed functional MRI (fMRI) on a patient with a mass lesion while she happened to experience a simple partial seizure. We used regional T2* signal changes to localize seizure-related hemodynamic changes. Seizure activity was associated with changes in MR signal in different regions that showed sequential activation and deactivation. Our study has shown that epileptic activity leads to changes in cerebral hemodynamics. In selected patients, therefore, it might be possible to use fMRI as a noninvasive tool to detect and investigate cortical patterns of activation associated with seizure activity.

引用

页码：524 / 527

页数：4

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