Pentoxifylline and antioxidants improve sperm quality in male patients with varicocele

被引:58
作者
Oliva, Alejandro [2 ]
Dotta, Alejandro [2 ]
Multigner, Luc [1 ,3 ]
机构
[1] Univ Rennes 1, INSERM, U625, F-35042 Rennes, France
[2] Hosp Italiano Rosario, Serv Urol, Unidad Androl, Rosario, Argentina
[3] INSERM, GERHM, F-75654 Paris 13, France
关键词
MALE-INFERTILITY; PART II; OLIGOASTHENOSPERMIA; PATHOPHYSIOLOGY; FERTILITY; TRIAL;
D O I
10.1016/j.fertnstert.2008.09.024
中图分类号
R71 [妇产科学];
学科分类号
100211 [妇产科学];
摘要
We examined the effect of 12 weeks of daily oral administration of pentoxifylline with zinc and folic acid on the semen quality of 36 men with varicocele-associated infertility in an open, uncontrolled study. After 4 weeks of treatment, the proportion of morphologically normal sperm cells was significantly increased; these changes persisted until at least 4 weeks after the end of treatment. (Fertil Steril (R) 2009;91:1536-9. (C)2009 by American Society for Reproductive Medicine.)
引用
收藏
页码:1536 / 1539
页数:4
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