Quantitative determination of sulfonamide residues in foods of animal origin by high-performance liquid chromatography with fluorescence detection

被引：107

作者：

Stoev, G ^{[1
]}

Michailova, A ^{[1
]}

机构：

[1] Cent Lab Vet Control & Ecol, Sofia 1528, Bulgaria

来源：

JOURNAL OF CHROMATOGRAPHY A | 2000年 / 871卷 / 1-2期

关键词：

residue determination; fluorescence detection; sulfonamide;

D O I：

10.1016/S0021-9673(99)00904-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An HPLC method with fluorescence detection is proposed for the quantitative determination of residues of ten of the most used sulfonamides as their derivatives. Sulfonamides were isolated from meat, mix meat and kidney with ethyl acetate (first extraction) and acetone (second extraction) and further purified by partitioning three times with water-methylene chloride. The recovery for mix meat spiked with 1, 5 and 10 mu g/kg of sulfonamides averaged 64%, 68% and 75%, respectively. Limits of quantitation were 1 mu g/kg for sulfaquinoxaline and 0.5 mu g/kg for the remaining sulfonamides. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：37 / 42

页数：6

共 15 条

[1] Abjean Jean Pierre, 1993, Journal of Planar Chromatography - Modern TLC, V6, P147
[2] Abjean JP, 1997, J AOAC INT, V80, P737
[3] AERTS MML, 1990, THESIS VRIJE U AMSTE
[4] SPECTROFLUOROMETRIC DETERMINATION OF PHARMACEUTICALS CONTAINING AROMATIC OR ALIPHATIC PRIMARY AMINO-GROUPS AS THEIR FLUORESCAMINE (FLURAM) DERIVATIVES
DESILVA, JAF
STROJNY, N
[J]. ANALYTICAL CHEMISTRY, 1975, 47 (04) : 714 - 718
[5] DISERENS JM, 1993, COMDMUNICATION
[6] Edder P., 1997, TRAV CHIM ALIMENT HY, V88, P554
[7] Gehring TA, 1997, J AOAC INT, V80, P751
[8] Gehring TA, 1995, J AOAC INT, V78, P1161
[9] HPLC determination of sulfadiazine residues in coho salmon (Oncorhynchus kisutch) with confirmation by liquid chromatography with atmospheric pressure chemical ionization mass spectrometry
Gehring, TA
Rushing, LG
Churchwell, MI
Doerge, DR
McErlane, KM
Thompson, HC
[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1996, 44 (10) : 3164 - 3169
[10] IMPROVEMENT OF CHEMICAL-ANALYSIS OF ANTIBIOTICS .17. APPLICATION OF AN AMINO CARTRIDGE TO THE DETERMINATION OF RESIDUAL SULFONAMIDE ANTIBACTERIALS IN MEAT, FISH AND EGG
IKAI, Y
OKA, H
KAWAMURA, N
HAYAKAWA, J
YAMADA, M
HARADA, KI
SUZUKI, M
NAKAZAWA, H
[J]. JOURNAL OF CHROMATOGRAPHY, 1991, 541 (1-2): : 393 - 400

← 1 2 →