Tumor metastasis: A new twist on epithelial-mesenchymal transitions

被引：127

作者：

Vernon, AE ^{[1
]}

LaBonne, C ^{[1
]}

机构：

[1] Northwestern Univ, Dept Biochem Mol Biol & Cell Biol, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA

来源：

CURRENT BIOLOGY | 2004年 / 14卷 / 17期

关键词：

D O I：

10.1016/j.cub.2004.08.048

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Epithelial-mesenchymal transitions are essential for normal embryonic development and for progression of non-invasive tumor cells into malignant, metastatic carcinomas. Twist, an important regulator of morphogenesis in the embryo, has recently been implicated in the onset of invasive behavior during tumor progression.

引用

页码：R719 / R721

页数：3

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