Influence of polymer surface hydrophilicity on albumin adsorption

被引：8

作者：

Henry, M ^{[1
]}

Bertrand, P ^{[1
]}

机构：

[1] Univ Catholique Louvain, PCPM, B-1348 Louvain, Belgium

来源：

SURFACE AND INTERFACE ANALYSIS | 2004年 / 36卷 / 08期

关键词：

ToF-SIMS; XPS; polycarbonate; albumin adsorption; surface hydrophilicity; principal component analysis;

D O I：

10.1002/sia.1748

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 [物理化学]; 081704 [应用化学];

摘要：

X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (ToF-SIMS) were used to characterize human serum albumin (HSA) adsorption on polycarbonate membranes: a native PC membrane (PC) and a hydrophilic treated one (PCox/PVP). Principal component analysis was used to reveal the difference in the amount of HSA adsorbed on the two substrates. The treated membrane was found to have a lower affinity for albumin than the native one. Copyright (C) 2004 John Wiley Sons, Ltd.

引用

页码：729 / 732

页数：4

共 7 条

[1]

Conformation change of albumin adsorbed on polycarbonate membranes as revealed by ToF-SIMS [J].