p-toluenesulfonic acid-catalyzed efficient synthesis of dihydropyrimidines:: Improved high yielding protocol for the Biginelli reaction

被引：109

作者：

Jin, TS ^{[1
]}

Zhang, SL ^{[1
]}

Li, TS ^{[1
]}

机构：

[1] Hebei Univ, Coll Chem & Environm Sci, Baoding 071002, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2002年 / 32卷 / 12期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1081/SCC-120004068

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Dihydropyrimidines are prepared by a one-pot cyclocondensation of aldehydes, beta-ketoesters and urea with p-toluenesulfonic acid-catalyzed condensation reaction. Yields are significantly higher than utilizing classical Biginelli reaction conditions.

引用

页码：1847 / 1851

页数：5

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