A concise synthesis of alpha-glycosyl cyanides

被引：14

作者：

Igarashi, Y ^{[1
]}

Shiozawa, T ^{[1
]}

Ichikawa, Y ^{[1
]}

机构：

[1] JOHNS HOPKINS UNIV,SCH MED,DEPT PHARMACOL & MOL SCI,BALTIMORE,MD 21205

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 05期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0960-894X(97)00059-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A simple procedure has been developed for the synthesis of alpha-glycosyl cyanides: reactions of O-benzylated ethyl 1-thio-glycosides of L-fucose and D-glucose, with TMSCN and MeOTf in ether exclusively gave the corresponding alpha-glycosyl cyanides in good yields. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：613 / 616

页数：4

共 28 条

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