Expression and characterization of flagella in nonmotile enteroinvasive Escherichia coli isolated from diarrhea cases

被引：18

作者：

Andrade, A

Girón, JA

Amhaz, JMK

Trabulsi, LR

Martinez, MB

机构：

[1] Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Anal Clin & Toxicol, Sao Paulo, Brazil

[2] Inst Butantan, Microbiol Lab, Sao Paulo, Brazil

[3] Benemerita Univ Autonoma Puebla, Inst Ciencias, Puebla 72000, Mexico

来源：

INFECTION AND IMMUNITY | 2002年 / 70卷 / 10期

关键词：

D O I：

10.1128/IAI.70.10.5882-5886.2002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report that enteroinvasive Escherichia coli (EIEC) serotypes considered to be nonmotile produce an unusually large (77 kDa) flagellin that is assembled into functional flagellum filaments that allow the bacteria to swim in modified motility agar. The EIEC flagellin showed N-terminal identity to most common enterobacterial flagellins, especially those of the E. coli H7 serotype. These data are important in terms of the epidemiology, evolution, and biology of EIEC.

引用

收藏

页码：5882 / 5886

页数：5

相关论文

共 32 条

[1] The role of flagella, but not fimbriae, in the adherence of Salmonella enterica serotype Enteritidis to chick gut explant [J].

Allen-Vercoe, E ;

Woodward, MJ .

JOURNAL OF MEDICAL MICROBIOLOGY, 1999, 48 (08) :771-780

[2] Characterization of enteroinvasive Escherichia coli and Shigella strains by RAPD analysis [J].

Bando, SY ;

do Valle, GRF ;

Martinez, MB ;

Trabulsi, LR ;

Moreira-Filho, CA .

FEMS MICROBIOLOGY LETTERS, 1998, 165 (01) :159-165

[3] Clonal relationships among Shigella serotypes suggested by cryptic flagellin gene polymorphism [J].

Coimbra, RS ;

Lefevre, M ;

Grimont, F ;

Grimont, PAD .

JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (02) :670-674

[4] PATHOGENESIS OF ESCHERICHIA-COLI DIARRHEA [J].

DUPONT, HL ;

FORMAL, SB ;

HORNICK, RB ;

SNYDER, MJ ;

LIBONATI, JP ;

SHEAHAN, DG ;

LABREC, EH ;

KALAS, JP .

NEW ENGLAND JOURNAL OF MEDICINE, 1971, 285 (01) :1-&

[5] SHIGELLA AND ENTEROINVASIVE ESCHERICHIA-COLI INFECTIONS IN HOUSEHOLDS OF CHILDREN WITH DYSENTERY IN BANGKOK [J].

ECHEVERRIA, P ;

SETHABUTR, O ;

SERICHANTALERGS, O ;

LEXOMBOON, U ;

TAMURA, K .

JOURNAL OF INFECTIOUS DISEASES, 1992, 165 (01) :144-147

[6]

Ewing WH., 1986, EDWARDS EWINGS IDENT, V4th

[7] IDENTIFICATION OF A COMMON ENTEROBACTERIAL FLAGELLIN EPITOPE WITH A MONOCLONAL-ANTIBODY [J].

FENG, P ;

SUGASAWARA, RJ ;

SCHANTZ, A .

JOURNAL OF GENERAL MICROBIOLOGY, 1990, 136 :337-342

[8] Molecular characterization of the gene encoding H antigen in Escherichia coli and development of a PCR-restriction fragment length polymorphism test for identification of E-coli O157:H7 and O157:NM [J].

Fields, PI ;

Blom, K ;

Hughes, HJ ;

Helsel, LO ;

Feng, P ;

Swaminathan, B .

JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (05) :1066-1070

[9] Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response [J].

Gewirtz, AT ;

Simon, PO ;

Schmitt, CK ;

Taylor, LJ ;

Hagedorn, CH ;

O'Brien, AD ;

Neish, AS ;

Madara, JL .

JOURNAL OF CLINICAL INVESTIGATION, 2001, 107 (01) :99-109

[10] EXPRESSION OF FLAGELLA AND MOTILITY BY SHIGELLA [J].

GIRON, JA .

MOLECULAR MICROBIOLOGY, 1995, 18 (01) :63-75

← 1 2 3 4 →