Neurotensin: an endogenous antipsychotic? Commentary

被引:50
作者
Kinkead, B [1 ]
Nemeroff, CB [1 ]
机构
[1] Emory Univ, Sch Med, Dept Psychiat & Behav Sci, Lab Neuropsychopharmacol, Atlanta, GA 30322 USA
关键词
D O I
10.1016/S1471-4892(01)00128-X
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Despite evidence from a variety of experimental approaches implicating the neuropeptide neurotensin in both the mechanism of action of antipsychotic drugs and the pathophysiology of schizophrenia, there has been some debate as to whether a peripherally administered neurotensin receptor agonist represents a sound strategy for the development of a novel class of antipsychotic drugs.
引用
收藏
页码:99 / 103
页数:5
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