Acute hepatitis B after autologous stem cell transplantation in a man previously infected by hepatitis B virus

被引:26
作者
Senecal, D
Pichon, E
Dubois, F
Delain, M
Linassier, C
Colombat, P
机构
[1] CHU Bretonneau, Dept Hematol & Oncol, F-37044 Tours, France
[2] CHU Bretonneau, Dept Virol, F-37044 Tours, France
关键词
autologous stem cell transplantation; hepatitis B virus;
D O I
10.1038/sj.bmt.1702039
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
We report a case of acute hepatitis B after autologous stem cell transplantation (ASCT) in a patient with low-grade non-Hodgkin's lymphoma. At diagnosis of the hematological disease, the patient had the characteristic serology of a previous hepatitis B infection, being Ag HBs negative, hepatitis B virus core antibody positive (anti-HBC) and hepatitis B virus surface antibody weakly positive. He developed fatal hepatitis B after autologous stem cell transplantation, suggesting reactivation consequent to immunosuppression.
引用
收藏
页码:1243 / 1244
页数:2
相关论文
共 8 条
  • [1] Reactivation of hepatitis B in a long-term anti-HBs-positive patient with AIDS following lamivudine withdrawal
    Altfeld, M
    Rockstroh, JK
    Addo, M
    Kupfer, B
    Pult, I
    Will, H
    Spengler, U
    [J]. JOURNAL OF HEPATOLOGY, 1998, 29 (02) : 306 - 309
  • [2] FAN FS, 1991, BONE MARROW TRANSPL, V8, P417
  • [3] Gangneux JP, 1996, BONE MARROW TRANSPL, V18, P1131
  • [4] LOCASCIULLI A, 1994, BONE MARROW TRANSPL, V14, P833
  • [5] LOCASCIULLI A, 1990, BONE MARROW TRANSPL, V6, P25
  • [6] FATAL REACTIVATION OF PRECORE MUTANT HEPATITIS-B VIRUS-ASSOCIATED WITH FIBROSING CHOLESTATIC HEPATITIS AFTER BONE-MARROW TRANSPLANTATION
    MCIVOR, C
    MORTON, J
    BRYANT, A
    COOKSLEY, WG
    DURRANT, S
    WALKER, N
    [J]. ANNALS OF INTERNAL MEDICINE, 1994, 121 (04) : 274 - 275
  • [7] VANDAM J, 1990, BONE MARROW TRANSPL, V5, P57
  • [8] WEBSTER A, 1989, BONE MARROW TRANSPL, V4, P207