To fuse and to protect. A novel role for CED-9 in mitochondrial morphology reveals an ancient function

被引:4
作者
Cipolat, S. [1 ]
Scorrano, L. [1 ]
机构
[1] Dulbecco Telethon Inst, Venetian Inst Mol Med, I-35129 Padua, Italy
关键词
D O I
10.1038/sj.cdd.4402005
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:1833 / 1834
页数:2
相关论文
共 22 条
[1]   Bax/Bak-dependent release promotes of DDP/TIMM8a promotes Drp1-mediated mitochondrial fission and mitoptosis during programmed cell death [J].
Arnoult, D ;
Rismanchi, N ;
Grodet, A ;
Roberts, RG ;
Seeburg, DP ;
Estaquier, J ;
Sheng, M ;
Blackstone, C .
CURRENT BIOLOGY, 2005, 15 (23) :2112-2118
[2]   Release of OPA1 during apoptosis participates in the rapid and complete release of cytochrome c and subsequent mitochondrial fragmentation [J].
Arnoult, D ;
Grodet, A ;
Lee, YJ ;
Estaquier, J ;
Blackstone, C .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (42) :35742-35750
[3]   Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development [J].
Chen, HC ;
Detmer, SA ;
Ewald, AJ ;
Griffin, EE ;
Fraser, SE ;
Chan, DC .
JOURNAL OF CELL BIOLOGY, 2003, 160 (02) :189-200
[4]   BCL-2, BCL-XL sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis [J].
Cheng, EHYA ;
Wei, MC ;
Weiler, S ;
Flavell, RA ;
Mak, TW ;
Lindsten, T ;
Korsmeyer, SJ .
MOLECULAR CELL, 2001, 8 (03) :705-711
[5]   OPA1 requires mitofusin 1 to promote mitochondrial fusion [J].
Cipolat, S ;
de Brito, OM ;
Dal Zilio, B ;
Scorrano, L .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (45) :15927-15932
[6]   Cell death: Critical control points [J].
Danial, NN ;
Korsmeyer, SJ .
CELL, 2004, 116 (02) :205-219
[7]   Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics [J].
Delivani, P ;
Adrain, C ;
Taylor, RC ;
Duriez, PJ ;
Martin, SJ .
MOLECULAR CELL, 2006, 21 (06) :761-773
[8]   Mitochondrial fission proteins regulate programmed cell death in yeast [J].
Fannjiang, Y ;
Cheng, WC ;
Lee, SJ ;
Qi, B ;
Pevsner, J ;
McCaffery, JM ;
Hill, RB ;
Basañez, G ;
Hardwick, JM .
GENES & DEVELOPMENT, 2004, 18 (22) :2785-2797
[9]   The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis [J].
Frank, S ;
Gaume, B ;
Bergmann-Leitner, ES ;
Leitner, WW ;
Robert, EG ;
Catez, F ;
Smith, CL ;
Youle, RJ .
DEVELOPMENTAL CELL, 2001, 1 (04) :515-525
[10]   Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis [J].
Germain, M ;
Mathai, JP ;
McBride, HM ;
Shore, GC .
EMBO JOURNAL, 2005, 24 (08) :1546-1556