Is there a negative correlation between explicit memory and hippocampal volume?

被引:37
作者
Chantôme, M
Perruchet, P
Hasboun, D
Dormont, D
Sahel, M
Sourour, N
Zouaoui, A
Marsault, C
Duyme, M
机构
[1] Univ Paris 07, INSERM, U155, Dept Biol Anthropol & Genet Epidemiol, F-75251 Paris 05, France
[2] Fac Sci, LEAD, F-21000 Dijon, France
[3] Univ Paris 06, Grp Hosp Pitie Salpetriere, Dept Neurol, F-75634 Paris 13, France
[4] Univ Paris 06, Grp Hosp Pitie Salpetriere, Dept Neuroradiol, F-75634 Paris 13, France
关键词
D O I
10.1006/nimg.1999.0486
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The aim of this research was to study the relationship between explicit memory and hippocampal volume. Seventy healthy adults were administered one implicit memory test and one explicit memory (EM) test and underwent magnetic resonance imaging. The major finding was a negative correlation between the EM test and the right hippocampus/brain volume ratio (t = -0.25, P = 0.03) and the left hippocampus/brain volume ratio (t = -0.27, P = 0.02), This finding is not consistent with pathologic findings, which tend to show a relationship between decrease in memory performance and hippocampal atrophy. This discrepancy is discussed, (C) 1999 Academic Press.
引用
收藏
页码:589 / 595
页数:7
相关论文
共 22 条
[1]   IMPLICIT AND EXPLICIT MEMORY IN ALZHEIMERS-DISEASE AND PARKINSONS-DISEASE [J].
BONDI, MW ;
KASZNIAK, AW .
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY, 1991, 13 (02) :339-358
[2]   Making memories: Brain activity that predicts how well visual experience will be remembered [J].
Brewer, JB ;
Zhao, Z ;
Desmond, JE ;
Glover, GH ;
Gabrieli, JDE .
SCIENCE, 1998, 281 (5380) :1185-1187
[3]   Imaging cognition: An empirical review of PET studies with normal subjects [J].
Cabeza, R ;
Nyberg, L .
JOURNAL OF COGNITIVE NEUROSCIENCE, 1997, 9 (01) :1-26
[4]   The functional neuroanatomy of episodic memory: The role of the frontal lobes, the hippocampal formation, and other areas [J].
Desgranges, B ;
Baron, JC ;
Eustache, F .
NEUROIMAGE, 1998, 8 (02) :198-213
[5]   Memory systems analyses of mnemonic disorders in aging and age-related diseases [J].
Gabrieli, JDE .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (24) :13534-13540
[6]  
GOLOMB J, 1994, LEARN MEMORY, V1, P45
[7]   LATERALIZED INCREASES IN CEREBRAL BLOOD-FLOW DURING PERFORMANCE OF VERBAL AND SPATIAL TASKS - RELATIONSHIP WITH PERFORMANCE-LEVEL [J].
GUR, RC ;
RAGLAND, JD ;
RESNICK, SM ;
SKOLNICK, BE ;
JAGGI, J ;
MUENZ, L ;
GUR, RE .
BRAIN AND COGNITION, 1994, 24 (02) :244-258
[8]  
Hasboun D, 1996, AM J NEURORADIOL, V17, P1091
[9]  
HASBOUN D, 1996, B MEM SOC ANTHRO PAR, V1, P43
[10]  
JESSELL TM, 1991, PRINCIPLES NEURAL SC, P929