Corneal ulcer caused by the new fungal species Sarcopodium oculorum

被引:18
作者
Guarro, J
Höfling-Lima, AL
Gené, J
De Freitas, D
Godoy, P
Zorat-Yu, ML
Zaror, L
Fischman, O
机构
[1] Univ Rovira & Virgili, Fac Med & Ciencies Salut, Dept Ciencies Med Basiques, Unite Microbiol, Tarragona 43201, Spain
[2] Univ Rovira & Virgili, Inst Estudis Avancats, Tarragona 43201, Spain
[3] UNIFESP, EPM, Disciplina Oftalmol, Sao Paulo, Brazil
[4] UNIFESP, EPM, Disciplina Biol Celular, Sao Paulo, Brazil
[5] Univ Austral Chile, Inst Clin Microbiol, Valdivia, Chile
关键词
D O I
10.1128/JCM.40.8.3071-3075.2002
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We describe a case of keratitis caused by a new species of the hyphomycetous genus Sarcopodium, S. oculorum. The corneal ulcer developed after 5 months of treatment with corticosteroids in a Brazilian boy diagnosed with allergic conjunctivitis. Fungal hyphae and conidia were detected in corneal scrapings, and repeated cultures were positive for this fungus. The infection was resolved with natamycin and ketoconazole. Eleven antifungals were tested against this fungus, and all except flucytosine and fluconazole showed in vitro activity.
引用
收藏
页码:3071 / 3075
页数:5
相关论文
共 12 条
[1]  
BEHRENSBRAUMANN W, 1999, DEV OPHTHALMOL, V32, P1
[2]  
de Hoog G.S., 2000, ATLAS CLIN FUNGI, VSecond
[3]  
Ellis MB, 1976, MORE DEMATIACEOUS HY, DOI DOI 10.1079/9780851983653.0000
[4]  
FOSTER CS, 1992, INFECT DIS CLIN N AM, V6, P851
[5]   A new Chaetomium from Thailand [J].
Gene, J ;
Guarro, J .
MYCOLOGICAL RESEARCH, 1996, 100 :1005-1009
[6]  
Guarro J, 2000, J CLIN MICROBIOL, V38, P2434
[7]   Mycotic keratitis due to Curvularia senegalensis and in vitro antifungal susceptibilities of Curvularia spp. [J].
Guarro, J ;
Akiti, T ;
Almada-Horta, R ;
Leite, LAM ;
Gené, J ;
Ferreira-Gomes, S ;
Aguilar, C ;
Ortoneda, M .
JOURNAL OF CLINICAL MICROBIOLOGY, 1999, 37 (12) :4170-4173
[8]  
National Committee for Clinical Laboratory Standards, 1998, M38P NAT COMM CLIN L
[9]   Comparison study of broth macrodilution and microdilution antifungal susceptibility tests for the filamentous fungi [J].
Pujol, I ;
Guarro, J ;
Llop, C ;
Soler, L ;
FernandezBallart, J .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (09) :2106-2110
[10]  
Schroers HJ, 1999, SYDOWIA, V51, P114