Efficient synthesis of functionalized organozinc compounds by the direct insertion of zinc into organic iodides and bromides

被引：386

作者：

Krasovskiy, Arkady ^{[1
]}

Malakhov, Vladimir ^{[1
]}

Gavryushin, Andrei ^{[1
]}

Knochel, Paul ^{[1
]}

机构：

[1] Univ Munich, Dept Chem & Biochem, D-81377 Munich, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 36期

关键词：

coupling; homogeneous catalysis; insertion; organozinc compounds; zinc;

D O I：

10.1002/anie.200601450

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Insider dealing: A wide range of poly-functional (hetero)aromatic and aliphatic zinc reagents can be easily prepared in THF. The compounds are formed by a Zn insertion reaction mediated by the addition of LiCl (see scheme; All = allyl). © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：6040 / 6044

页数：5

共 27 条

[1] [Anonymous], METAL CATALYZED CROS
[2] ACTIVATED METALS - PROCEDURE FOR PREPARATION OF ACTIVATED MAGNESIUM AND ZINC
ARNOLD, RT
KULENOVIC, ST
[J]. SYNTHETIC COMMUNICATIONS, 1977, 7 (03) : 223 - 232
[3] New efficient preparation of functionalized arylzinc or thienylzinc compounds from aryl or thienyl chlorides using cobalt catalysis
Gosmini, C
Amatore, M
Claudel, S
Périchon, J
[J]. SYNLETT, 2005, (14) : 2171 - 2174
[4] Functionalized arylzinc compounds in ethereal solvent: Direct synthesis from aryl iodides and zinc powder and application to Pd-catalyzed reaction with allylic halides
Ikegami, R
Koresawa, A
Shibata, T
Takagi, K
[J]. JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (06) : 2195 - 2199
[5] New progress in the cobalt-catalysed synthesis of aromatic organozinc compounds by reduction of aromatic halides by zinc dust
Kazmierski, I
Gosmini, C
Paris, JM
Périchon, J
[J]. TETRAHEDRON LETTERS, 2003, 44 (34) : 6417 - 6420
[6] SYNTHESIS AND REACTIVITY TOWARD ACYL CHLORIDES AND ENONES OF THE NEW HIGHLY FUNCTIONALIZED COPPER REAGENTS RCU(CN)ZNI
KNOCHEL, P
YEH, MCP
BERK, SC
TALBERT, J
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (10) : 2390 - 2392
[7] Knochel P., 1999, ORGANOZINC REAGENTS
[8] Knochel P., 1994, ORGANOCOPPER REAGENT, P85
[9] Knochel P, 2005, HANDBOOK OF FUNCTIONALIZED ORGANOMETALLICS: APPLICATIONS IN SYNTHESIS, P251
[10] A LiCl-mediated Br/Mg exchange reaction for the preparation of functionalized aryl- and heteroarylmagnesium compounds from organic bromides
Krasovskiy, A
Knochel, P
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (25) : 3333 - 3336

← 1 2 3 →