Asymmetric functionalization of nanoparticles based on thermally addressable DNA interconnects

被引:104
作者
Huo, Fengwei
Lytton-Jean, Abigail K. R.
Mirkin, Chad A.
机构
[1] Northwestern Univ, Dept Chem, Evanston, IL 60208 USA
[2] Northwestern Univ, Int Inst Nanotechnol, Evanston, IL 60208 USA
关键词
D O I
10.1002/adma.200601178
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The synthesis of nanoparticles asymmetrically functionalized with oligonucleotides is reported. The method provides excellent control over the placement of oligonucleotides on the surface of only one hemisphere of each particle (see figure). This new synthetic capability allows one to introduce valency into such structures and then use that valency to direct particle-assembly events.
引用
收藏
页码:2304 / +
页数:4
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