Radical-scavenging activities of new megastigmane glucosides from Macaranga tanarius (L.) MULL.-ARG.

被引：42

作者：

Matsunami, Katsuyoshi

Takamori, Ichiko

Shinzato, Takakazu

Aramoto, Mitsunori

Kondo, Kazunari

Otsuka, Hideaki

Takeda, Yoshio

机构：

[1] Hiroshima Univ, Grad Sch Biomed Sci, Dept Pharmacognosy, Minami Ku, Hiroshima 7348553, Japan

[2] Univ Ryukyus, Fac Agr, Subtrop Field Sci Ctr, Okinawa 9030129, Japan

[3] Univ Ryukyus, Trop Biosphere Res Ctr, Iriomote Stn, Okinawa 9071541, Japan

[4] Natl Inst Hlth Sci, Div Foods, Tokyo 1588501, Japan

[5] Univ Tokushima, Fac Integrated Arts & Sci, Tokushima 7708502, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2006年 / 54卷 / 10期

关键词：

Macarunga tanarius; Euphorbiaceae; megastigmane glucoside; macarangioside; 2,2-diphenyl-picrylhydrazyl (DPPH);

D O I：

10.1248/cpb.54.1403

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Four new megastigmane glucosides, named macarangiosides A-D (2-5), together with mallophenol B, lauroside E, methyl brevifolin carboxylate, and hyperin and isoquercitrin as a mixture were isolated from the leaves of Macaranga tanarius (L.) MULL.-ARG. (Euphorbiaceae). Their structures were elucidated by spectroscopic and chemical analyses. Macarangioside A-C (2-4) and mallophenol B were galloylated on glucose moiety and possessed the potent 2,2-diphenyl-pierylhydrazyl (DPPH) radical-scavenging activity.

引用

页码：1403 / 1407

页数：5

共 16 条

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