IL-9 in allergic inflammation

被引：67

作者：

Hauber, HP ^{[1
]}

Bergeron, C ^{[1
]}

Hamid, Q ^{[1
]}

机构：

[1] McGill Univ, Meakins Christie Labs, Montreal, PQ H2X 2P2, Canada

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY | 2004年 / 134卷 / 01期

关键词：

allergy; asthma; inflammation; interleukin-9;

D O I：

10.1159/000078384

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Th2 type cytokines such as interleukin (IL)-4, IL-5, IL-9, and IL-13 are important mediators in allergic inflammation. The present review will focus on the role of IL-9 in allergic inflammation. The structure and genomic architecture of IL-9 and its receptor, the source of IL-9 and its regulation as well as its effects on different cell types will be reviewed. Furthermore, the specific role of IL-9 in allergic diseases and the potential therapeutic approach of blocking IL-9 will be discussed. Copyright (C) 2004 S. Karger AG, Basel.

引用

页码：79 / 87

页数：9

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