Asymmetric synthesis of (R)-sulcatol

被引：20

作者：

Davies, SG

Smyth, GD

机构：

[1] Dyson Perrins Laboratory, University of Oxford, Oxford OX1 3QY, South Parks Road

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 04期

关键词：

D O I：

10.1016/0957-4166(96)00103-6

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The insect pheromone (R)-sulcatol, 2-hydroxy-6-methylhept-5-ene, is synthesised via a stereoselective conjugate addition of (R)-lithium N,alpha-dimethylbenzylamide to tert-butyl (E,E)-hexa-2,4-dienoate, Grignard addition, and stereospecific Meisenheimer rearrangement. Hydrogenation of the olefin, dehydration of the tertiary alcohol and N-O bond cleavage complete the synthesis. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：1005 / 1006

页数：2

共 7 条

[1] GNATHOTRICHUS-SULCATUS - SYNERGISTIC RESPONSE TO ENANTIOMERS OF AGGREGATION PHEROMONE SULCATOL [J].