Studies on the chemistry of thienoannelated O,N- and S,N-containing heterocycles.: 24.: Synthesis of imidazo[1,5-d]thieno[2,3-b][1,4]thiazine derivatives as potential receptor ligands

被引：2

作者：

Erker, T ^{[1
]}

Handler, N ^{[1
]}

机构：

[1] Univ Vienna, Inst Pharmaceut Chem, A-1090 Vienna, Austria

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2002年 / 39卷 / 04期

关键词：

D O I：

10.1002/jhet.5570390407

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile synthesis of the imidazo[1,5-d]thieno[2,3-b][1,4]thiazine ring system is described. Reaction of 6-benzyl-2,3-dihydro-1H-thieno[2,3-b][1,4]thiazine-2-one (1) with potassium tert-butoxide and diethylchlorophosphate gave intermediate 2 which resulted in the disired ring system after adding the corresponding isocyanides and potassium tert-butoxide.

引用

页码：645 / 648

页数：4

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