Molecular mechanisms of B-lymphocyte transformation by Epstein-Barr virus

被引：28

作者：

Bishop, GA

Busch, LK

机构：

[1] Univ Iowa, Dept Microbiol, Iowa City, IA 52242 USA

[2] Univ Iowa, Dept Internal Med, Iowa City, IA 52242 USA

[3] Univ Iowa, Grad Program Mol Biol, Iowa City, IA 52242 USA

[4] Vet Affairs Med Ctr, Iowa City, IA 52242 USA

来源：

MICROBES AND INFECTION | 2002年 / 4卷 / 08期

关键词：

B lymphocyte; Epstein-Barr virus; cell transformation; signal transduction; lymphoma;

D O I：

10.1016/S1286-4579(02)01605-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The B-lymphotropic virus Epstein-Barr virus (EBV) has been implicated in the pathogenesis of B-cell malignancies, particularly in immunodeficient individuals. This review provides a brief overview of the EBV-encoded proteins involved in B-cell transformation, and the current state of knowledge about their roles in this process. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

收藏

页码：853 / 857

页数：5

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