Cellular absorption of electric field energy: influence of molecular properties of the cytoplasm

被引：40

作者：

Simeonova, M

Wachner, D

Gimsa, J

机构：

[1] Univ Rostock, Fachbereich Biol, D-18057 Rostock, Germany

[2] Humboldt Univ, Inst Biol, D-10115 Berlin, Germany

来源：

BIOELECTROCHEMISTRY | 2002年 / 56卷 / 1-2期

关键词：

molecular dispersions; human red blood cells; hemoglobin; ellipsoidal single shell model; single cell dielectric spectroscopy;

D O I：

10.1016/S1567-5394(02)00010-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Molecular dispersions may significantly alter the frequency dependence of structural polarizations. Consequently, the molecular properties cannot be neglected when the energy absorption is calculated with a subcellular resolution. Our example presents calculations that explain the absorption in single human red blood cells. The molecular properties of the cytoplasm have been derived from literature data on the impedance of Hb suspensions. The resulting cell properties were then compared to own data obtained by single cell dielectric spectroscopy. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：215 / 218

页数：4

共 11 条

[1] A polarization model overcoming the geometric restrictions of the laplace solution for spheroidal cells: Obtaining new equations for field-induced forces and transmembrane potential [J].