Lithium perchlorate mediated three-component preparation of α-aminonitriles under solvent-free conditions

被引:13
作者
Azizi, N [1 ]
Saidi, MR [1 ]
机构
[1] Sharif Univ Technol, Dept Chem, Tehran, Iran
关键词
lithium perchlorate; alpha-aminonitriles; solvent-free conditions; three-component condensation;
D O I
10.1081/SCC-120030307
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A three-component reaction between aliphatic or aromatic aldehyde, an amine and trimethylsilyl cyanide mediated by solid LiClO4, gave amino nitriles in good to excellent yields. The reaction proceeded smoothly under solvent-free conditions without any side products.
引用
收藏
页码:1207 / 1214
页数:8
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