Prevalence of pelvic Paget's disease of bone in the United States

被引:85
作者
Altman, RD
Bloch, DA
Hochberg, MC
Murphy, WA
机构
[1] Univ Miami, Sch Med, Dept Vet Affairs Med Ctr, Educ & Clin Ctr, Miami, FL USA
[2] Stanford Univ, Sch Med, Dept Biostat, Stanford, CA USA
[3] Univ Maryland, Dept Med, Baltimore, MD 21201 USA
[4] Univ Maryland, Dept Epidemiol & Prevent Med, Baltimore, MD 21201 USA
[5] Univ Texas, MD Anderson Canc Ctr, Dept Diagnost Imaging, Houston, TX 77030 USA
关键词
Paget's disease of bone; epidemiology; prevalence; osteitis deformans;
D O I
10.1359/jbmr.2000.15.3.461
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The objective of this article was to estimate the prevalence of Paget's disease of bone in the United States from a statistically derived sample of the general population. Pelvic radiographs obtained in the First National Health and Nutrition Examination Survey (NHANES-I) were reviewed for the presence of Paget's disease. Age, sex, and geographic distribution of Paget's disease of the pelvic region were determined. The overall prevalence of Paget's disease in the United States was estimated. Pelvic Paget's disease is estimated to be present in 0.71 + 0.18% of the radiographs of the general population. The disease was higher in frequency in people who were in the older decades of life with the highest prevalence of 2.32 + 0.54 % in the 65- to 74-year-old people. There is a slight male predominance in the 45- to 74-year age group. The regional distribution suggests the highest prevalence in the Northeast (1.48 + 0.52%) with the lowest prevalence in the South (0.26+0.25%). The prevalence was equal in white people and black people. An estimate of the overall prevalence of Paget's disease in the United States was at least 1% and perhaps as much as 2% of the general population with near equal sex distribution and the highest prevalence in the northeastern United States.
引用
收藏
页码:461 / 465
页数:5
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