In vivo and in vitro immunomodulatory activities of Trichilia glabra aqueous leaf extracts

被引：34

作者：

Benencia, F ^{[1
]}

Courrèges, MC ^{[1
]}

Coulombié, FC ^{[1
]}

机构：

[1] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Virol Lab, Dpto Quim Biol, RA-1428 Buenos Aires, DF, Argentina

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2000年 / 69卷 / 03期

关键词：

Trichilia glabra; leaf extract; mouse; immunomodulatory effect; delayed-type hypersensitivity response; antibodies;

D O I：

10.1016/S0378-8741(99)00010-0

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The effects of Trichilia glabra (Meliaceae) aqueous leaf extract on mouse lymphocytes were studied. The in vitro proliferation of T and B lymphocytes was completely impaired. Besides, the extract significantly diminished both antibody and delayed hypersensitivity responses in treated mice. These results suggest that the extract exerts a marked immunomodulatory effect on the murine immune system. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：199 / 205

页数：7

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