Signaling mechanism of the AT2 angiotensin II receptor: Crosstalk between AT1 and AT2 receptors in cell growth

被引：54

作者：

Horiuchi, M ^{[1
]}

Lehtonen, JYA

Daviet, L

机构：

[1] Ehime Univ, Sch Med, Dept Med Biochem, Shigenobu, Ehime 79102, Japan

[2] Univ Helsinki, Cent Hosp, Dept Surg, Div Vasc Surg, Helsinki, Finland

[3] Inst Pasteur, INSERM, U163, F-75724 Paris, France

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1999年 / 10卷 / 10期

关键词：

D O I：

10.1016/S1043-2760(99)00191-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The peptide angiotensin (Ang) II exerts a range of actions in the cardiovascular, renal reproductive and central nervous systems. At least two distinct Ang II receptor subtypes have been defined and designated as type 1 (AT1) and type 2 (AT2). The function and signaling mechanism of these receptor subtypes are quite different, and these receptors exert opposite effects on cell growth.

引用

页码：391 / 396

页数：6

共 44 条

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