Regio- and enantioselective iridium-catalyzed allylic alkylation with in situ activated P,C-chelate complexes

被引：133

作者：

Lipowsky, G ^{[1
]}

Miller, N ^{[1
]}

Helmchen, G ^{[1
]}

机构：

[1] Heidelberg Univ, Inst Organ Chem, D-69120 Heidelberg, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 35期

关键词：

alkylation; allylic substitution; asymmetric catalysis; iridium; phosphorus amidites;

D O I：

10.1002/anie.200460016

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Come together: Successful cooperation of iridium and copper yielded a new catalyst system for allylic alkylation. Branched alkylation products can be obtained rapidly and with high enantioselectivity from simple linear precursors (see scheme; cod = cyclooctadiene).

引用

页码：4595 / 4597

页数：3

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