Biomaterials for orbital implants and ocular prostheses: Overview and future prospects

被引：82

作者：

Baino, Francesco ^{[1
]}

Perero, Sergio ^{[1
,2
]}

Ferraris, Sara ^{[1
]}

Miola, Marta ^{[1
]}

Balagna, Cristina ^{[1
]}

Verne, Enrica ^{[1
]}

Vitale-Brovarone, Chiara ^{[1
]}

Coggiola, Andrea ^{[3
]}

Dolcino, Daniela ^{[3
]}

Ferraris, Monica ^{[1
]}

机构：

[1] Politecn Torino, Appl Sci & Technol Dept, Inst Mat Phys & Engn, Turin, Italy

[2] Ist Super Mario Boella, Turin, Italy

[3] Azienda Osped Nazl SS Antonio & Biagio & Cesare A, SOC Oculist, Alessandria, Italy

来源：

ACTA BIOMATERIALIA | 2014年 / 10卷 / 03期

关键词：

Orbital implant; Ocular prosthesis; Enucleation; Porous biomaterials; Antibacterial properties; GLASS-CERAMIC SCAFFOLDS; POROUS POLYETHYLENE MEDPOR; RESONANCE-IMAGING ASSESSMENT; MOTILITY COUPLING POST; IN-VITRO BIOACTIVITY; TERM FOLLOW-UP; FIBROVASCULAR INGROWTH; INTRAORBITAL IMPLANTS; RABBIT MODEL; CORALLINE HYDROXYAPATITE;

D O I：

10.1016/j.actbio.2013.12.014

中图分类号：

R318 [生物医学工程];

学科分类号：

100103 [病原生物学];

摘要：

The removal of an eye is one of the most difficult and dramatic decisions that a surgeon must consider in case of severe trauma or life-threatening diseases to the patient. The philosophy behind the design of orbital implants has evolved significantly over the last 60 years, and the use of ever more appropriate biomaterials has successfully reduced the complication rate and improved the patient's clinical outcomes and satisfaction. This review provides a comprehensive picture of the main advances that have been made in the development of innovative biomaterials for orbital implants and ocular prostheses. Specifically, the advantages, limitations and performance of the existing devices are examined and critically compared, and the potential of new, smart and suitable biomaterials are described and discussed in detail to outline a forecast for future research directions. (C) 2013 Acts Materialia Inc. Published by Elsevier Ltd. All rights reserved.

引用

页码：1064 / 1087

页数：24

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