Electrophilic amination of carbanions by N-carboxamido oxaziridines

被引：29

作者：

Armstrong, A ^{[1
]}

Atkin, MA

Swallow, S

机构：

[1] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

[2] Roche Discovery Welwyn, Welwyn Garden City AL7 3AY, Herts, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 13期

基金：

英国工程与自然科学研究理事会;

关键词：

amination; oxaziridines; carbanions; amino acids and derivatives; ureas;

D O I：

10.1016/S0040-4039(00)00140-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A range of 3-aryl-N-carboxamido oxaziridines have been prepared and tested as reagents for electrophilic amination of carbanions. The 3-(2-cyanophenyl)-derivative gave highest yields of amination product, and was used for amination of ketone, eater and amide enolates, as well as sulfone-, phosphonate- and nitrile-stabilized carbanions. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：2247 / 2251

页数：5

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