A new selective synthesis of the Ile-allo-Thr-Gly tripeptide fragment of lysobactin

被引：26

作者：

Armaroli, S

Cardillo, G

Gentilucci, L

Gianotti, M

Tolomelli, A

机构：

[1] Univ Bologna, Dipartimento Chim G Ciamician, I-40126 Bologna, Italy

[2] Univ Bologna, CSFM, CNR, I-40126 Bologna, Italy

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 08期

关键词：

D O I：

10.1021/ol005659o

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

trans-Aziridine-2-carboxylic acid derivatives are useful intermediates for the synthesis of threonine or allo-threonine through ring expansion and S(N)2 displacement, respectively. We describe here the preparation of the Ile-allo-Thr-Gly 11 fragment of Lysobactin via the aziridine 9 intermediate.

引用

页码：1105 / 1107

页数：3

共 19 条

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