Enantio-dependence of inducer-specific bidirectional regulation of tumor necrosis factor (TNF)-alpha production: Potent TNF-alpha production inhibitors

被引：17

作者：

Miyachi, H ^{[1
]}

Azuma, A ^{[1
]}

Hioki, E ^{[1
]}

Iwasaki, S ^{[1
]}

Hashimoto, Y ^{[1
]}

机构：

[1] UNIV TOKYO,INST MOL & CELLULAR BIOSCI,BUNKYO KU,TOKYO 113,JAPAN

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 19期

关键词：

D O I：

10.1016/0960-894X(96)00409-X

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

In optically active phthalimide analogs of thalidomide, the inducer-specific TNF-alpha production-enhancing and -inhibiting activities are separated. This implies that the target molecules of the two activities are different. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：2293 / 2298

页数：6

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