Cisplatin contamination observed on the outside of drug vials

被引：39

作者：

Nygren, O

Gustavsson, B

Ström, L

Friberg, A

机构：

[1] Natl Inst Working Life, Program Chem Exposure Assessment, SE-90713 Umea, Sweden

[2] Ostra Hosp, Dept Surg, SE-41685 Gothenburg, Sweden

[3] Ostra Hosp, Hosp Pharm, SE-41685 Gothenburg, Sweden

来源：

ANNALS OF OCCUPATIONAL HYGIENE | 2002年 / 46卷 / 06期

关键词：

cytotoxic drugs; vial contamination; cisplatin;

D O I：

10.1093/annhyg/mef074

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Exposure to cytotoxic drugs is of great concern today. Special regulations for handling these drugs during preparation and administration have been implemented in most countries. Concern has also been raised as to whether exposure to these drugs can occur due to contaminated drug vials. In this investigation, wipe samples were taken from drug vials used for platinum-containing drugs, e.g. cisplatin and related drugs. The vials were randomly picked from unbroken packages from different manufacturers. The results showed that drug vials may already be contaminated on the outside when delivered from the manufacturer.

引用

页码：555 / 557

页数：3

共 14 条

[1] Monitoring occupational exposure to cancer chemotherapy drugs [J].