The SLICC/ACR damage index: progress report and experience in the field

被引:85
作者
Gladman, DD [1 ]
Urowitz, MB [1 ]
机构
[1] Univ Toronto, Toronto Western Hosp, Ctr Prognosis Studies Rheumat Dis, Hlth Network, Toronto, ON M52 2S8, Canada
关键词
SLICC/ACR; damage index; prognosis; outcome; SLE;
D O I
10.1191/096120399680411335
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The SLICC/ACR damage index for SLE was developed to assess accumulated damage since the onset of the disease. The damage includes non-reversible changes in organs and systems affected by the disease process itself its therapy, or inter-current illness. This paper describes the development of the damage index, its validation and its use. It is recommended as an outcome measure for longitudinal studies of prognosis and response to new therapies, and as a stratification measure for clinical trials.
引用
收藏
页码:632 / 637
页数:6
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